Which complication is associated with malpositioning of a UVC?

Malpositioning of a umbilical venous catheter (UVC) can lead to serious complications, and one of the most critical is hepatic necrosis. When the catheter is incorrectly positioned, it may end up in the liver or its blood supply. This can obstruct normal blood flow and introduce toxic substances directly into the liver, potentially leading to ischemic injury and subsequent cell death, known as hepatic necrosis.

This condition is particularly concerning because the liver plays a crucial role in metabolism and detoxification, and damage to this organ can precipitate various systemic issues, affecting the overall health of the neonate. Inadequate blood flow can lead to tissue hypoxia and result in significant liver damage, which necessitates prompt identification and resolution of the catheter's placement issue to prevent irreversible damage.

While malpositioning can increase infection risk or lead to other complications, hepatic necrosis directly correlates with incorrect placement in a manner that can cause immediate and severe repercussions for the patient's health.