Which maternal medication can cause hyperinsulinemia in the fetus?

The medication that can cause hyperinsulinemia in the fetus is beta-sympathomimetics. These medications, commonly used for their bronchodilator effects, can stimulate the beta-adrenergic receptors, leading to increased insulin secretion. This is particularly significant during pregnancy, as elevated levels of circulating insulin can result in hyperinsulinemia in the fetus, which may influence fetal growth and metabolism.

Beta-sympathomimetics are sometimes prescribed to manage conditions such as asthma or preterm labor, and their potential effects on insulin regulation need to be monitored. This hyperinsulinemia can contribute to other complications, including macrosomia (excessive fetal growth), which may complicate delivery and have implications for maternal health as well.

While insulin is essential for managing diabetes during pregnancy, it does not cause hyperinsulinemia in the fetus as it is used to correct hyperglycemia rather than induce an increase in insulin levels. Thiazide diuretics and beta blockers do not have a direct relationship with fetal insulin secretion and therefore do not typically induce hyperinsulinemia.