Which of the following is a non-pharmacologic measure for pain control in infants?

Non-nutritive sucking is a recognized non-pharmacologic measure for pain control in infants. This technique involves allowing infants to suck on a pacifier or their own fingers, which can provide comfort and help in managing pain. The act of sucking activates a natural soothing response and can release endorphins, which are the body's own pain-relieving chemicals. It helps distract infants from painful stimuli and contributes to their overall sense of security and well-being during potentially distressing procedures.

In contrast, the other options involve pharmacologic interventions. Oral morphine and IV opioids are both forms of medication that are used to manage pain but do not fall under non-pharmacologic measures. Sucrose solution, while helpful in some contexts for pain relief, particularly during procedures, is often classified as a mild analgesic but not strictly a non-pharmacologic measure as it relies on sugar's effects rather than behavioral techniques. Therefore, non-nutritive sucking is seen as a purely non-invasive, supportive approach to alleviate pain in infants.